High Blood Pressure
High blood pressure is the single most important factor affecting cardiovascular health, as it places strain on arteries and contributes to long-term challenges with circulation and heart function.
According to the CDC, 47.7% of U.S. adults have elevated blood pressure, with prevalence increasing with age:
18–39 years old: 23.4%
40–59 years old: 52.5%
60+ years old: 71.6%
Tikva Heart contains 16 clinically studied nutrients that have been researched for their role in supporting healthy blood pressure, including:
Nitrosigine®, Pomegranate, CoQ10, Magnesium, Vitamin E, L-Theanine, Flaxseed Powder, L-Taurine, Grape Seed Extract, L-Citrulline, Inositol, Vitamin B2, Vitamin B3, Vitamin B6, Vitamin C, and Zinc.
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High Cholesterol
High cholesterol is one of the most common cardiovascular factors, affecting nearly 94 million U.S. adults — many of whom are unaware because it often has no symptoms.
Cholesterol includes two types: LDL (“bad” cholesterol), which can contribute to plaque buildup in arteries, and HDL (“good” cholesterol), which helps remove excess cholesterol.
Among LDL particles, small dense LDL (sd-LDL) is considered the most concerning, as it is more prone to oxidation and linked to long-term cardiovascular challenges.
👉 Not all cholesterol is bad. In fact, targeting all cholesterol the same way — as many statin drugs do — may not be the best answer. What really matters is supporting healthy balance, lowering the most harmful forms like sd-LDL, and protecting beneficial cholesterol like HDL. You can read more in our article: The Cholesterol Controversy: Why the Real Danger Isn’t What You’ve Been Told.
Supporting healthy cholesterol balance — especially maintaining lower levels of sd-LDL — is an important part of overall cardiovascular wellness.
Tikva Heart contains 21 clinically studied nutrients researched for their role in supporting healthy cholesterol metabolism and overall heart health, including:
Citrus Bergamot, Vitamin B5 (Pantothenic Acid), Coenzyme Q10, Vitamin B3 (Niacin), Chromium, Nitrosigine® (L-Arginine), Pomegranate, Flax Seed, L-Carnitine, Alpha Lipoic Acid, Inositol, Vitamin B12, Chromium, Zinc, Magnesium, Selenium, Copper, Betaine, L-Taurine, L-Citrulline, Grape Seed Extract
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Nitric oxide (Poor Circulation)
Nitric oxide is essential for healthy circulation and blood flow, helping arteries expand, contract, and stay flexible. But starting in your 30s, nitric oxide production drops by about 20% per decade — and by age 65, most people have lost up to 85% of their ability to produce it.
Many turn to beetroot powders as a solution, but their high oxalate content can cause problems for some people. That’s why Tikva Heart uses 10 clinically researched nutrients to support nitric oxide production and stability — without the oxalates.
Tikva Heart includes 10 nutrients studied for their role in supporting nitric oxide and circulation health:
Nitrosigine®, L-Citrulline, Pomegranate, L-Carnitine, Vitamin C, L-Taurine, L-Theanine, Inositol, Coenzyme Q-10, and Alpha Lipoic Acid.
Read More & See Clinical Research – Click Here
Atherosclerosis (Hardening of Arteries)
Atherosclerosis: The Silent Factor Behind Heart Attacks and Strokes
Atherosclerosis — the buildup of plaque in arteries — is the underlying factor in most heart attacks and strokes. It often begins in childhood and progresses silently for decades, usually going undetected until a serious event occurs.
The process develops in stages: changes to the artery wall (influenced by factors such as LDL cholesterol, toxins, or high blood pressure), formation of fatty streaks, plaque growth, and eventually plaque rupture. A ruptured plaque can trigger a blood clot, leading to a heart attack or stroke.
Because the condition often progresses without symptoms until arteries are significantly narrowed, supporting vascular health early is key.
Tikva Heart contains 19 clinically studied nutrients researched for their role in supporting healthy arteries, vascular flexibility, and circulation — including:
Pomegranate, Grape Seed Extract, CoQ10, Magnesium, Zinc, Selenium, Vitamin D, L-Citrulline, Nitrosigine®, and Citrus Bergamot.
Read More & See Clinical Research – Click Here
Coronary artery disease (CAD)
Coronary Artery Disease (CAD): The Leading Cause of Heart Attacks
CAD is the most common type of heart-related condition in the U.S., affecting 18.2 million adults and contributing to nearly 647,000 deaths annually. Every 40 seconds, someone in America experiences a heart attack.
CAD develops when plaque builds up in the arteries that supply oxygen-rich blood to the heart. Over time, this narrowing reduces blood flow and can lead to chest discomfort, shortness of breath, and, eventually, serious cardiovascular events.
Contributing factors include cholesterol imbalance, high blood pressure, smoking, and blood sugar issues — with plaque buildup often beginning in childhood.
Supporting long-term cardiovascular wellness means focusing on healthy blood pressure, cholesterol balance, circulation, and overall vascular health.
Tikva Heart contains 13 clinically studied nutrients researched for their role in supporting healthy arteries and circulation, including:
Citrus Bergamot, Pomegranate, Flax Seed Powder, Nitrosigine®, L-Carnitine, Alpha Lipoic Acid, Inositol, Vitamin B12, Vitamin C, Vitamin D, Chromium, Zinc, and Boron.
Read More & See Clinical Research – Click Here
High glucose (blood sugar) levels and insulin
Blood Sugar & Heart Health
Elevated blood sugar, common in diabetes and metabolic syndrome, is a key factor that affects cardiovascular wellness. It can contribute to artery narrowing, promote inflammation and oxidative stress, and increase harmful small dense LDL cholesterol — all of which place strain on the heart and circulation.
Supporting healthy blood sugar balance through lifestyle habits and targeted nutrition is an important part of long-term cardiovascular health.
Tikva Heart contains 11 clinically studied nutrients researched for their role in supporting healthy blood sugar metabolism and cardiovascular wellness, including:
Chromium, Vitamin D, L-Carnitine, Coenzyme Q10, Magnesium, Alpha Lipoic Acid, Zinc, Manganese, L-Taurine, Nitrosigine® (L-Arginine), Citrus Bergamot.
Read More & See Clinical Research – Click Here
Blood Clots (Deep vein thrombosis)
Venous Thromboembolism (VTE): Understanding Circulation Challenges
Venous thromboembolism (VTE), commonly known as blood clots, includes two related conditions: deep vein thrombosis (DVT) and pulmonary embolism (PE).
Deep vein thrombosis (DVT): when a clot forms in a deep vein, usually in the leg, thigh, or pelvis.
Pulmonary embolism (PE): when a clot breaks loose and travels through the bloodstream to the lungs.
While these events are medical conditions that require treatment, supporting circulation, vascular health, and blood flow through nutrition and lifestyle is an important part of overall cardiovascular wellness.
Tikva Heart contains 10 clinically studied nutrients researched for their role in supporting circulation, vascular flexibility, and healthy blood flow, including:
Vitamin E, Pomegranate, Coenzyme Q10 (CoQ10), Grape Seed Extract, L-Arginine (Nitrosigine®), Vitamin C, Vitamin D, Magnesium, L-Taurine, and Alpha Lipoic Acid (ALA).
Read More & See Clinical Research – Click Here
Triglycerides
Triglycerides & Heart Health
Triglycerides are fats that come from the food we eat and circulate in our blood. Elevated triglycerides, especially when combined with high LDL (“bad”) cholesterol and low HDL (“good”) cholesterol, can negatively impact cardiovascular wellness over time.
Supporting healthy triglyceride balance is an important part of overall heart health.
Tikva Heart contains 10 clinically studied nutrients researched for their role in supporting healthy triglyceride metabolism and cardiovascular wellness, including:
Citrus Bergamot, Flax Seed Powder, L-Theanine, Niacin, and Vitamin D.
We also recommend pairing Tikva Heart with a high-quality fish oil supplement for additional triglyceride support. We didn’t include fish oil directly in Tikva Heart because it can oxidize and affect taste, but it makes an excellent companion nutrient.
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C-reactive protein (Inflammation)
Chronic Inflammation: The Hidden Driver of Heart Problems
High levels of C-reactive protein (CRP) in the blood are often used as a marker of chronic inflammation. When inflammation lingers, it can place stress on cells and tissues throughout the body — including the heart and blood vessels. Over time, this ongoing inflammation is recognized as a major factor that affects long-term cardiovascular health.
Supporting a healthy inflammatory response is essential for protecting your heart.
Tikva Heart contains 9 clinically studied nutrients researched for their role in promoting a healthy inflammatory response and supporting cardiovascular wellness, including:
Coenzyme Q10, Vitamin C, Vitamin A, Vitamin D, Vitamin E, Magnesium, L-Theanine, Zinc, Citrus Bergamot.
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Stress
Stress and Your Heart
In addition to the emotional toll, stress triggers a physical reaction in the body. Hormones like adrenaline and cortisol are released into the bloodstream, preparing us for “fight or flight.” This response makes the heart beat faster and constricts blood vessels, which can temporarily raise blood pressure and place added strain on the cardiovascular system.
Supporting relaxation and resilience to stress is an important part of overall heart health.
Tikva Heart contains 7 clinically studied nutrients researched for their role in promoting calm, relaxation, and cardiovascular support, including:
L-Theanine, Vitamin B1, Vitamin B5, Vitamin B6, Vitamin B12, Inositol, and Magnesium.
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Atrial fibrillation and arrhythmia
Arrhythmia and Heart Rhythm
An arrhythmia is an irregular rhythm in the heartbeat. Atrial fibrillation (AF) is the most common form, where the atria (the upper chambers of the heart) beat irregularly instead of contracting efficiently. This can affect blood flow and, in some cases, contribute to additional cardiovascular complications.
While arrhythmias are medical conditions that require proper diagnosis and care, supporting your heart’s natural rhythm and energy production through nutrition is an important part of overall cardiovascular wellness.
Tikva Heart contains 4 clinically studied nutrients researched for their role in supporting heart rhythm, relaxation, and cellular energy, including:
Magnesium, CoQ10, L-Taurine, and L-Carnitine.
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High Homocysteine & Oxidative Stress levels (Damage To Blood vessels)
Homocysteine, Oxidative Stress & Your Heart
Elevated homocysteine and oxidative stress often work together, amplifying their impact on the body. High homocysteine can contribute to the production of reactive oxygen species (ROS), which worsens oxidative stress and puts strain on blood vessels.
👉 Elevated homocysteine is a risk factor that can lead to or worsen damage to blood vessels if not kept in balance.
Together, homocysteine and oxidative stress can weaken blood vessel walls, affect endothelial function, and promote inflammation — factors that may make arteries more vulnerable over time.
Supporting healthy homocysteine metabolism and antioxidant defenses is an important part of long-term cardiovascular wellness.
Tikva Heart contains 13 clinically studied nutrients researched for their role in supporting homocysteine balance, oxidative stress defense, and vascular health, including:
Vitamin B6, Vitamin B12, Zinc, Betaine, Vitamin B2, Magnesium, Vitamin C, Vitamin E, Selenium, Alpha Lipoic Acid, Coenzyme Q10, Grape Seed Extract, and Pomegranate.
Read More & See Clinical Research – Click Here