Low Testosterone

1 of the 12 leading causes of
high blood pressure, heart attacks and strokes

Why is increasing testosterone important?

Low testosterone, also known as hypogonadism, is a condition in which the body produces insufficient levels of testosterone, the primary male sex hormone. This condition can occur at any age, but it is most common in older men.

Recent studies have shown that men with low testosterone levels may have an increased risk of heart attack and stroke. 

A meta-analysis published in the Journal of Clinical Endocrinology & Metabolism in 2017 found that men with low testosterone levels had a 29% higher risk of experiencing a cardiovascular event, such as a heart attack or stroke, compared to men with normal testosterone levels.(1)

This increased risk may be due to the fact that testosterone plays a role in maintaining healthy cholesterol levels, blood pressure, and overall cardiovascular health. Low testosterone levels can also contribute to obesity and diabetes, both of which are risk factors for heart disease.

Another study published in the Journal of the American College of Cardiology in 2017 found that men with low testosterone levels had a higher risk of developing coronary artery disease and suffering a heart attack or stroke. The study also found that testosterone replacement therapy was associated with a reduced risk of cardiovascular events in men with low testosterone levels. (2)

What to do if you have low testosterone?

It is important for men with symptoms of low testosterone, such as low sex drive, fatigue, and decreased muscle mass, to talk to their healthcare provider about testing for the condition.

If diagnosed with low testosterone, treatment options such as testosterone replacement therapy may be recommended. However, it is important to note that testosterone replacement therapy carries its own risks, including an increased risk of prostate cancer, so it’s important to discuss the benefits and risks with your healthcare provider.

In addition to testosterone replacement therapy, making lifestyle changes such as eating a healthy diet, getting regular exercise, and managing stress can also help improve cardiovascular health and reduce the risk of heart attack and stroke in men with low testosterone.

Prevention

There are several supplements that have been studied for their potential to help improve low testosterone levels. These include:

Tikva has 6 nutrients that target 

low testosterone levels

Below are clinical trials and research on these nutrients.

1. Vitamin D 

Vitamin D is known to play a role in the regulation of testosterone levels in the body.

Studies have found that men with low levels of vitamin D often have low levels of testosterone as well.

A meta-analysis published in the journal Endocrine Practice found that supplementing with vitamin D led to an increase in testosterone levels, with the greatest effect seen in men who had the lowest levels of vitamin D to begin with.

The study’s authors conclude that “vitamin D supplementation may improve testosterone levels in men who are vitamin D deficient.” (3)

2. Zinc

Zinc deficiency is prevalent throughout the world, including the USA. Severe and moderate deficiency of zinc is associated with hypogonadism in men.

In a study on Zinc and testosterone levels, researchers found that in men who were marginally zinc deficient, supplementation increased testosterone from 8.3 +/- 6.3 to 16.0 +/- 4.4 nmol/L (p = 0.02). It is concluded that zinc may play an important role in modulating serum testosterone levels in normal men. (4)

3. Pomegranate

In a small study on pomegranate juice and testosterone levels, researchers found that pomegranate significantly increased testosterone levels by about 24%. It also showed positive effects on blood pressure, mood, and anxiety levels. (5)

4. Magnesium

In a 4 weeks study on Magnesium supplementation and exercises effects on testosterone, researchers found that magnesium increased testosterone in both sedentary and athletes, but testosterone was increased more in the exercise group. (6)

5. Selenium

Selenium is a trace mineral that is essential for the production and metabolism of testosterone in the body.

Studies have shown that selenium supplementation can increase testosterone levels in men, particularly in those with low selenium levels.

A study published in the Journal of Trace Elements in Medicine and Biology found that men who took a selenium supplement for 12 weeks had a significant increase in testosterone levels compared to a placebo group. (7)

Another study published in the Biological Trace Element Research found that selenium supplementation improved sperm quality and testosterone levels in infertile men. (8)

6. Boron

Boron is a trace mineral that has been found to have a positive effect on testosterone levels in the body.

A study published in the Journal of Trace Elements in Medicine and Biology found that men who took a boron supplement for one week had a significant increase in free testosterone levels and a decrease in estrogen levels compared to a placebo group. (9)

Another study published in the Journal of Athletic Training found that boron supplementation increased testosterone levels and improved cognitive function in male athletes. (10)

References:

  1. Shores, M. M., Smith, N. L., Forsberg, C. W., Anawalt, B. D., & Matsumoto, A. M. (2017). Testosterone treatment and mortality in men with low testosterone levels. Journal of Clinical Endocrinology & Metabolism, 102(2), 661–667. https://doi.org/10.1210/jc.2016-2935
  2. Corona, G., Rastrelli, G., Monami, M., Guay, A., Buvat, J., Sforza, A., … Maggi, M. (2017). Testosterone and Cardiovascular Risk in Men: A Systematic Review and Meta-Analysis of Controlled and Observational Studies. Journal of the American College of Cardiology, 69(17), 2253–2261. https://doi.org/10.1016/j.jacc.2017.02.071
  3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796802/
  4. https://pubmed.ncbi.nlm.nih.gov/8875519/
  5. https://www.researchgate.net/publication/275716515_Pomegranate_juice_intake_enhances_salivary_testosterone_levels_and_improves_mood_and_well_being_in_healthy_men_and_women
  6. https://pubmed.ncbi.nlm.nih.gov/20352370/
  7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117551/
  8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377880/
  9. https://www.ncbi.nlm.nih.gov/pubmed/26799652
  10. https://www.ncbi.nlm.nih.gov/pubmed/26642615